Which statement about zero-order release is true?

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Multiple Choice

Which statement about zero-order release is true?

Explanation:
Zero-order release means the drug leaves the dosage form at a constant amount per unit time, regardless of how much drug remains in the system. This constant release rate is what defines zero-order kinetics, producing a straight-line release profile over time. The other ideas describe different behavior: release that slows as the remaining drug declines corresponds to first-order kinetics, and claiming the mechanism is driven only by the dissolved-drug concentration gradient oversimplifies zero-order systems, which are engineered to maintain a steady rate rather than be dictated solely by a gradient.

Zero-order release means the drug leaves the dosage form at a constant amount per unit time, regardless of how much drug remains in the system. This constant release rate is what defines zero-order kinetics, producing a straight-line release profile over time. The other ideas describe different behavior: release that slows as the remaining drug declines corresponds to first-order kinetics, and claiming the mechanism is driven only by the dissolved-drug concentration gradient oversimplifies zero-order systems, which are engineered to maintain a steady rate rather than be dictated solely by a gradient.

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