Which parameter is used to assess weight uniformity of tablets?

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Multiple Choice

Which parameter is used to assess weight uniformity of tablets?

Explanation:
Weight uniformity measures how close each tablet’s weight is to the batch mean. It directly checks dosing consistency, since tablets that weigh more or less than the target can contain more or less active drug, leading to variable patient doses. This is distinct from thickness (tablet size), hardness (crushing strength), and friability (tendency to crumble); none of those directly assess how much drug is in each individual tablet. In practice, a sample of tablets is weighed, and each weight is compared to the mean to ensure all are within the specified tolerance, reflecting proper blending and compression during manufacturing.

Weight uniformity measures how close each tablet’s weight is to the batch mean. It directly checks dosing consistency, since tablets that weigh more or less than the target can contain more or less active drug, leading to variable patient doses. This is distinct from thickness (tablet size), hardness (crushing strength), and friability (tendency to crumble); none of those directly assess how much drug is in each individual tablet. In practice, a sample of tablets is weighed, and each weight is compared to the mean to ensure all are within the specified tolerance, reflecting proper blending and compression during manufacturing.

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