Two well-known superdisintegrants are Acusol and Expotab.

• A. True
• B. False
• C. Not Sure
• D. Not Applicable

Answer: (A)

Superdisintegrants function by rapidly taking up water and swelling or by promoting capillary wicking, which breaks apart the tablet to speed up dissolution. Expotab is a classic brand name for sodium starch glycolate, a well-known disintegrant that swells quickly upon contact with gastric fluids. The other major, widely used superdisintegrant is croscarmellose sodium, sold under brands like Ac-Di-Sol; it is a crosslinked cellulose derivative that also swells and draws water into the tablet matrix to promote disintegration. If Acusol is interpreted as a variant spelling of Ac-Di-Sol, the statement is accurate: both Expotab (sodium starch glycolate) and Ac-Di-Sol (croscarmellose sodium) are well-known superdisintegrants.