In wet granulation, making the powder heavier makes for easier compression.

• A. True
• B. False
• C. Not enough data
• D. It depends on moisture content

Answer: (A)

In wet granulation, binding liquid turns powder into granules that are denser and more cohesive than the untreated powder. When the powder is heavier, the resulting granules tend to have higher bulk density, pack more tightly in the die, and present more robust interparticle contacts. Under compression, these denser granules deform and bond more readily, so a solid compact forms with less effort. The moisture acts as the binder, creating liquid bridges between particles and increasing cohesion, which further aids compaction when the granules are heavier. If moisture is excessive, stickiness can offset the benefit, but with appropriate moisture levels the increased density from heavier powder makes compression easier.