An order initiates Propofol at 10 mcg/kg/min for a 180 lb patient using a 1000 mg/100 mL lipid emulsion. What is the rate in mL/hr?

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Multiple Choice

An order initiates Propofol at 10 mcg/kg/min for a 180 lb patient using a 1000 mg/100 mL lipid emulsion. What is the rate in mL/hr?

Explanation:
Infusion rate calculation from weight-based dosing and drug concentration. Convert weight to kilograms: 180 lb ≈ 81.63 kg. Apply the dose: 10 mcg/kg/min × 81.63 kg = 816.3 mcg/min = 0.8163 mg/min. Know the concentration: 1000 mg/100 mL = 10 mg/mL. Convert to volume rate: 0.8163 mg/min ÷ 10 mg/mL = 0.08163 mL/min. Change to per hour: 0.08163 mL/min × 60 = 4.8978 mL/hr ≈ 4.9 mL/hr. The rate is about 4.9 mL/hr.

Infusion rate calculation from weight-based dosing and drug concentration.

Convert weight to kilograms: 180 lb ≈ 81.63 kg.

Apply the dose: 10 mcg/kg/min × 81.63 kg = 816.3 mcg/min = 0.8163 mg/min.

Know the concentration: 1000 mg/100 mL = 10 mg/mL.

Convert to volume rate: 0.8163 mg/min ÷ 10 mg/mL = 0.08163 mL/min.

Change to per hour: 0.08163 mL/min × 60 = 4.8978 mL/hr ≈ 4.9 mL/hr.

The rate is about 4.9 mL/hr.

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